Christian-Albrechts-Universität zu Kiel

The Faculty of Medicine of the Christian-Albrechts-University Kiel (CAU) is associated with Germany’s 2nd largest University Hospital (UKSH), and has a strong research focus on inflammatory diseases and precision medicine. The Institute of Clinical Molecular Biology (ICMB) at the University Kiel is a recognised leader in translational genomic research in inflammatory barrier diseases. Main interests are in the complex interactions between human barrier organs and the environment in health and disease. This includes the generation of genetic risk maps and biomarker detection using cohort-based approaches as well as research on epigenetic/transcriptomal alterations and their validation in cell biological experiments in vitro, in standardised mouse models in vivo. The institute operates the largest university based next generation sequencing centre in Germany, commands a high throughput genotyping facility and is partner in the popgen biobank program with more than 80.000 patients in Schleswig-Holstein under long-term follow up. The Department of Dermatology and Allergy is an international leader in molecular research on inflammatory skin diseases, and combines the clinical study of new therapeutics with laboratory studies of immunopathogenic mechanisms in human cells and tissues. The ultimate aim is to translate research findings into the human diagnostic or therapeutic experiment.

Role within ImmUniverse

CAU coordinates retrospective and prospective deep molecular profiling in work package 2, and coordinates and conducts a large-scale prospective open label clinical study on ulcerative colitis and atopic dermatitis with advanced biosampling in work package 6.